Daniel J Klionsky Selected Research

Phosphatidylinositols (Phosphatidylinositol)

1/2023	Autophagy and cancer drug resistance in dialogue: Pre-clinical and clinical evidence.
1/2023	Copper metabolism in cell death and autophagy.
11/2022	Autophagopathies: from autophagy gene polymorphisms to precision medicine for human diseases.

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Daniel J Klionsky Research Topics

Disease

42	Starvation 01/2023 - 02/2003
33	Neoplasms (Cancer) 03/2024 - 07/2011
6	Infections 01/2023 - 01/2009
5	Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular) 01/2023 - 11/2016
5	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 01/2007
4	Adenocarcinoma 03/2024 - 01/2021
4	Parkinson Disease (Parkinson's Disease) 10/2023 - 12/2016
4	Hypoxia (Hypoxemia) 01/2022 - 01/2016
4	COVID-19 12/2020 - 12/2020
3	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 09/2023 - 01/2020
3	Pancreatic Neoplasms (Pancreatic Cancer) 01/2023 - 01/2021
2	Macular Degeneration (Age-Related Maculopathy) 05/2024 - 01/2023
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 03/2024 - 11/2022
2	Mouth Neoplasms (Oral Cancer) 03/2024 - 01/2023
2	Inflammation (Inflammations) 02/2024 - 10/2017
2	Obesity 02/2024 - 11/2021
2	Bites and Stings (Sting) 12/2023 - 01/2019
2	Ischemia 10/2023 - 01/2021
2	Carcinogenesis 01/2023 - 01/2018
2	Choroidal Neovascularization 01/2023 - 01/2015
2	Pancreatitis 01/2023 - 01/2023
2	Hepatocellular Carcinoma (Hepatoma) 11/2022 - 10/2008

Drug/Important Bio-Agent (IBA)

40	Proteins (Proteins, Gene)FDA Link 03/2024 - 12/2006
20	NitrogenIBA 01/2023 - 02/2003
12	Phosphotransferases (Kinase)IBA 03/2024 - 10/2006
11	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2024 - 01/2021
11	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 10/2023 - 01/2019
8	Chloroquine (Aralen)FDA LinkGeneric 03/2024 - 12/2020
8	Sirolimus (Rapamycin)FDA Link 03/2024 - 01/2015
8	Beclin-1IBA 03/2024 - 06/2014
8	Proton-Translocating ATPases (ATPase, H+)IBA 10/2023 - 01/2019
7	IronIBA 01/2023 - 01/2018
7	Messenger RNA (mRNA)IBA 12/2020 - 07/2015
6	AMP-Activated Protein KinasesIBA 03/2024 - 01/2017
6	Carrier Proteins (Binding Protein)IBA 03/2024 - 07/2015
6	UbiquitinIBA 03/2024 - 01/2021
6	Adenosine Triphosphatases (ATPase)IBA 01/2023 - 07/2013
6	Amino Acids FDA Link 01/2022 - 12/2006
5	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 03/2024 - 01/2021
5	Proteasome Endopeptidase Complex (Proteasome)IBA 10/2023 - 01/2016
5	HMGB1 Protein (HMG1)IBA 01/2023 - 12/2016
5	Glucose (Dextrose)FDA LinkGeneric 01/2023 - 11/2015
4	Glutathione (Reduced Glutathione)IBA 03/2024 - 01/2019
4	Transcription Factors (Transcription Factor)IBA 03/2024 - 01/2021
4	Mechanistic Target of Rapamycin Complex 1IBA 03/2024 - 07/2011
4	CytokinesIBA 02/2024 - 11/2021
4	Phospholipid Hydroperoxide Glutathione PeroxidaseIBA 01/2023 - 01/2021
4	Vacuolar Proton-Translocating ATPases (V-Type ATPase)IBA 01/2023 - 01/2019
4	Protein AggregatesIBA 01/2022 - 01/2007
3	LipidsIBA 05/2024 - 01/2020
3	Malondialdehyde (Propanedial)IBA 03/2024 - 01/2021
3	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 03/2024 - 01/2021
3	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 03/2024 - 12/2020
3	Peptide Initiation Factors (Initiation Factor)IBA 03/2024 - 01/2019
3	Prokaryotic Initiation Factor-2IBA 03/2024 - 01/2023
3	Autophagy-Related Protein-1 HomologIBA 03/2024 - 01/2021
3	NF-kappa B (NF-kB)IBA 03/2024 - 01/2023
3	Mitogen-Activated Protein KinasesIBA 03/2024 - 01/2023
3	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 03/2024 - 11/2021
3	DNA (Deoxyribonucleic Acid)IBA 12/2023 - 11/2015
3	Phospholipids (Phosphatides)FDA LinkGeneric 10/2023 - 01/2020
3	Class III Phosphatidylinositol 3-KinasesIBA 10/2023 - 01/2021
3	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 10/2023 - 01/2021
3	phosphatidylethanolamineIBA 01/2023 - 12/2020
3	InterleukinsIBA 01/2023 - 12/2020
3	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2023 - 11/2022
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2023 - 12/2020
3	Fatty Acids (Saturated Fatty Acids)IBA 01/2021 - 01/2020
3	InflammasomesIBA 01/2019 - 12/2016
2	Green Fluorescent ProteinsIBA 03/2024 - 01/2022
2	Immune Checkpoint InhibitorsIBA 03/2024 - 01/2021
2	Transforming Growth Factor beta (TGF-beta)IBA 03/2024 - 01/2023
2	LigandsIBA 03/2024 - 12/2023
2	Activating Transcription Factor 4IBA 03/2024 - 01/2023
2	ClusterinIBA 03/2024 - 01/2023
2	Immunoglobulin G (IgG)IBA 03/2024 - 10/2005
2	Cisplatin (Platino)FDA LinkGeneric 03/2024 - 02/2024
2	AutoantibodiesIBA 02/2024 - 10/2005
2	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 10/2023 - 01/2023
2	Amyloid beta-Protein Precursor (Amyloid Protein Precursor)IBA 10/2023 - 01/2021
2	Basic-Leucine Zipper Transcription FactorsIBA 10/2023 - 01/2023
2	Presenilin-1IBA 10/2023 - 01/2021
2	Histone Deacetylases (Histone Deacetylase)IBA 01/2023 - 01/2022
2	tetrathiomolybdate (ammonium tetrathiomolybdate)IBA 01/2023 - 01/2023
2	GTP Phosphohydrolases (GTPases)IBA 01/2023 - 01/2019
2	tetraethylenepentamineIBA 01/2023 - 01/2023
2	Chelating AgentsIBA 01/2023 - 01/2018
2	CalciumIBA 01/2023 - 01/2023
2	gamma-Aminobutyric Acid (GABA)IBA 01/2023 - 01/2021
2	CopperIBA 01/2023 - 01/2023
2	Peroxidase (Myeloperoxidase)IBA 01/2023 - 01/2023
2	AntioxidantsIBA 01/2023 - 01/2021
2	Cyclin-Dependent Kinase Inhibitor p27IBA 01/2023 - 01/2019
2	Triethylenephosphoramide (TEPA)IBA 01/2023 - 01/2023
2	Lysosomal-Associated Membrane Protein 2IBA 01/2023 - 01/2021
2	Lipoxygenase (Lipoxygenase-1)IBA 01/2023 - 01/2021
2	Coenzyme A Ligases (Acid-Thiol Ligases)IBA 01/2023 - 01/2023

Therapy/Procedure

17	Therapeutics 03/2024 - 01/2016
4	Drug Therapy (Chemotherapy) 02/2024 - 01/2022
2	Immunotherapy 01/2023 - 01/2021